The article presents the results of scientific research aimed at reducing the personnel deficit, which poses a threat to ensuring Russia's technological sovereignty in the period of digital transformation and large-scale economic sanctions. The leading role of human capital and its improvement for the socio-economic development of the country is shown. On the basis of the quantitative assessment of the personnel deficit, the causes of the imbalance in the labor market in various sectors of the economy are identified. Traditional approaches to solving the problem of exceeding the demand for labor by the value of its supply in the labor market are examined. The role of maintaining the population, health and well-being of citizens in solving the personnel problem is shown. The issues of development of the system of training and retraining of personnel, adaptation of engineering education to the real needs of industry as the primary national development goals are considered. It is shown that a complex system of motivation, attraction and retention of qualified personnel works in the information economy. The limits and risks of the main directions of the reduction of the personnel deficit were identified. The analysis of the possibilities of using new digital technologies, including artificial intelligence, to realize the strategic interests of companies in the labor market is presented. The main tasks of personnel policy to ensure the competitive advantages of Russian companies in the context of systemic imbalances in the labor market have been identified.